Endocrine Abstracts

A 36 year old man presented with a six month history of palpitations. An ECG in a different hospital had showed a sinus tachycardia. An echocardiogram had also been performed and reported as normal. There were no apparent clinical features to suggest Cushing’s Syndrome (BMI 26 kg/m2). Resting pulse was 86/min. BP was 140/90. Examination was otherwise unremarkable.Baseline biochemical and haematological investigations including TFT, FBC we...

Self-monitoring of blood glucose (SMBG) is an important part of diabetes management but only provides a snapshot view of the blood sugar at that point in time. Technology such as Freestyle Libre and Continuous Glucose Monitoring (CGM) provides blood glucose readings and trends whilst omitting the more traditional method of multiple daily blood testing, and they have been reported in clinical trials to reduce hypoglycaemia, and improve blood sugar management day to day...

Ongoing patient engagement and education are vital in establishing successful self-management, long-term glycaemic management and a complication-free future for people with diabetes. Today’s healthcare requires engaging the current generations where approximately 71% of adults go online everyday, and an additional 11% go online three to five times per week. One in three young people currently use social media in their daily lives. Social media has brought about a major ch...

Congenital adrenal hyperplasia (CAH) is an autosomal recessive condition which leads to glucocorticoid deficiency. During childhood, aims of treatment are to prevent adrenal crisis and to achieve optimal adult height and normal puberty. In adults, aims of treatment are to prevent adrenal crisis, ensure normal fertility and avoid long-term consequences of glucocorticoid use. Current regimens with glucocorticoids cannot optimally replicate the normal physiological cortisol level...

Background: The Freestyle Flash glucose monitoring (Flash GM) is a new technology suitable for children and adolescents with Type 1 Diabetes Mellitus (T1DM). Clinical accuracy, safety and user acceptability of the Flash GM has been demonstrated in a recent study. In 2017 the UK Association of children’s diabetes clinicians (ACDC) launched national guidelines for training healthcare professionals in delivering Flash GM to children with T1DM.Objective...

Continuous glucose monitoring (CGM) allows continuous real-time blood glucose monitoring and informs users of blood glucose trend data and alarms which warn users of high or low blood glucose readings. Current evidence suggests that CGM can reduce episodes of hypoglycaemia in conditions such as congenital hyperinsulinism and metabolic disorders. Hypoglycaemia secondary to these conditions is serious with almost 50% of children demonstrating neurological impairments as a result...

Introduction: Primary hyperparathyroidism (PHPT) is usually caused by a single hyperfunctioning parathyroid adenoma. Preoperative localization studies allow for minimally invasive surgical removal. We present a case of PHPT caused by a solitary adenoma that could not be localised pre-operatively and review existing and emerging localisation modalities.Case report: A 65-year-old Chinese lady admitted for neck of femur fracture was found to have hypercalca...

Stem cell transplants are used to treat and cure many types of haematological malignancies as well as rare solid-organ tumours. The conditioning regimes, medications and potential graft vs host disease can have effects on many organ systems in the body. The Endocrinology Department has designed a follow-up service over the past 3 years for patients in remission due to increasing awareness of the potential endocrinological and metabolic effects of allogenic stem cell transplant...

Background: The different changes are seen on skin and it’s accessories in patients (pts) with Type 2 Diabetes (T2D); some of them represent the prognostic indicator of complicated diabetes and some directly contribute in development of them. The aim of our study was to examine the prevalence of characteristic changes of skin and its accessories in T2D considering the grade of severity of Diabetic Peripheral Neuropathy (DPN).Materials and methods: T...

The use of digital technology to improve accessibility and efficiency of services has been recognised and telemedicine has been increasing over recent years, particularly for patients with chronic conditions such as diabetes. The onset of the COVID-19 global pandemic rapidly accelerated the use of virtual consultations into everyday practice. The aim of this study was to assess feedback from paediatric diabetes patients and their parents regarding virtual consultations. The st...